We had an interview with Dr. Marjan Assefi Expert in The Research World

We Asked from Dr. Marjan Assefi PhD of Nano Biology and Doctor of Healthcare Administration, about important of Nanotechnology on Brain Injuries:

She said: Nano-drug delivery as a therapy for brain tumors is an advanced field in the field of precise targeted drug delivery methodologies. Nanodrug delivery circumvents unsolved problems associated with chemotherapy, other invasive therapeutic procedures, and various disorders presented by biological barriers. Recent dramatic developments in nanotechnology have produced many nanodevices that can be used against cancer. Invasion, regulation of the blood-brain barrier, camouflage from immune defense mechanisms, and specific targeting of cancer cells are some of the attractive features of nano device. One type of nanoparticles involves the use of liposomes as drug molecule carriers.

Liposomes are composed of vesicular bilayers, lamellae, composed of biocompatible and biodegradable lipids such as sphingomyelin, phosphatidylcholine and glycerophospholipids. Cholesterol, a type of lipid, is also commonly incorporated into lipid nanoparticle formulations. Cholesterol can increase liposome stability and prevent bilayer leakage. This is because its hydroxyl group can interact with the polar head of bilayer phospholipids. Liposomes have the potential to protect drugs from degradation, reach their targets, and reduce toxicity and side effects. This process can eventually form a uniform dispersion of small droplets within a liquid substance by breaking up the particles until the desired concentration is reached. It is already scaled up and used in industry, making it more attractive to researchers and the drug delivery industry. Liposomes can also be functionalized by attaching different ligands to their surface to enhance their delivery to the brain.

At last, she said: polymer Nanoparticles have properties that make them suitable for drug delivery, such as: Controlled drug release and targeting efficiency. It has been widely used in the development of drug delivery vehicles that cross the blood-brain barrier. Dr. Marjan Assefi, is doing research and working in the Nanotechnology and Neuroscience, she believes these two areas is the bridge between medical and science. She believes with Nanotechnology we will have very bright future if we use the Artificial Intelligence/ technology in a correct way.